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Dose translation remains a major challenge, because extrapolating nanomaterial pharmacokinetics from preclinical animals to humans can be confounded not only by body-size relationships, but also by interspecies differences in anatomy, physiology, immunology, and mononuclear phagocyte system function

In the present study MSG caused a significant increase in renal expression of KIM-1 and NGAL as well as increased serum concentrations of BUN, uric acid, and creatinine

doi: 10.1074/jbc.RA119.009592 146 RobinsonKMJanesMSPeharMMonetteJSRossMFHagenTMet al

(PubMed) Bouchemal N, Ouss L, Brassier A, et al

Lipid peroxides and peroxy radicals derived from polyunsaturated fatty acid chains are one of the executors of cellular ferroptosis [51]
