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In the TNT (Treating to New Targets) trial with 9572 patients with CAD,5 every 1-SD increase in LDL-C variability independently increased the risk of any coronary event by 16%, any cardiovascular event by 11%, death by 23%, myocardial infarction by 10%, and stroke by 17%

In addition, secondary causes of HTG should always be excluded when first evaluating a patient

[DOI] [PMC free article] [PubMed] [Google Scholar] Busceti CL, Biagioni F, Riozzi B, Battaglia G, Storto M, Cinque C, Molinaro G, Gradini R, Caricasole A, Canudas AM, et al

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