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Knocking down ARG2 in breast cancer cells significantly inhibits cell proliferation and causes G 2 /M arrest, without compensation through the OAT pathway (Roci et al., 2019)

Iron homeostasis Iron is required for ROS production, changing cellular labile iron pool (LIP) content, and altering the sensitivity of ferroptosis [14]
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Glutathione is also safe for most people, though mild digestive upset or rare allergic reactions can occur
