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10.1056/NEJM200008033430506 [DOI] [PubMed] [Google Scholar] 58.Hansson GK, Libby P, Schnbeck U, Yan ZQ

There's also a mild physiological case: some repair and detox processes are more active during sleep

Mayer-Barber KD, Andrade BB, Oland SD, Amaral EP, Barber DL, Gonzales J, Derrick SC, Shi R, Kumar NP, Wei W, et al

THE TARGET CONCENTRATION APPROACH TO DESIGNING A RATIONAL DOSAGE REGIMEN A rational dosage regimen is based on the assumption that there is a target concentration that will produce the desired therapeutic effect

One classification framework parallels that used in hearing loss, distinguishing conductive tinnitus from sensorineural tinnitus
