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Pharmacokinetic characteristics Absorption and distribution 30 minutes after intramuscular injection, the peak blood concentration of the drug is reached, with a bioavailability of 82% to 88%

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The British Obesity and Metabolic society recommend intramuscular injection of vitamin B 12 should be taken every three weeks in RYGB and BPD/DS patients, since the deficiency of B 12 still exists in the presence of higher doses of the oral supplement [120]

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For patients without neurological involvement, this is given three times weekly for two weeks