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One possible explanation for the absence of a clear G4 signature is intercalation of the small molecule into the RNA, as planar cationic aromatics are known to partially intercalate into non-G4 RNAs 40,41

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Atherosclerosis is a degenerative disease of elastic and large muscular arteries manifesting as atheromatous changes in the tunica intima and thickening of the vessel wall via accumulation of plasma lipids (especially cholesterol) and connective extracellular matrix (ECM) (collagen fibers and proteoglycans) as well as the migration of cells (smooth muscle cells, monocytes/macrophages), which is accompanied by proliferation, calcification, ulceration, hemorrhage, and thrombosis formation

DSIP, on the other hand, has been studied for its ability to increase the duration of delta sleep, which is a key component of restorative sleep