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Symptoms of Vitamin B12 Deficiency Vitamin B12 deficiency develops gradually, as the body's liver stores can sustain normal function for several years before depletion becomes clinically apparent

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Biotin deficiency is rare but can cause issues such as hair loss, skin problems, and neurological symptoms

It is important that the test is performed before participants are treated for B12 deficiency in order to detect an increase in serum holoTC