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People who have had surgery to remove the stomach or the end of the small intestine may also not be able to absorb vitamin B12
When Trx is in a reduced state, Trx-(SH) 2 , the two active-site cysteines form a dithiol group that is able to catalyze the reduction of disulfides in a number of proteins

doi: 10.1006/bbrc.1999.1272

However, chronic or excessive inflammation shifts the balance toward tissue destruction

[PMC free article] [PubMed] [Google Scholar] 10.Cloninger C.R
