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Conversely, augmented ferroptosis may sensitize aggressive forms of liver cancers (e.g., HCC, et al.) in conventional chemotherapy regimens

This further confirms that the enhancement of Nrf2 is a viable strategy for activating the GSH system

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Doses used clinically generally start modestly and can be adjusted upward based on the patient, with the intravenous route favored precisely because it sidesteps the oral-absorption question