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Kobayashi M, Suhara T, Baba Y, Kawasaki NK, Higa JK, Matsui T

While both GHRH and PACAP exert equipotent action regulating GH in amphibians and reptiles, in birds and mammals, PACAP only plays a secondary role, with GHRH being the main GH stimulator in those groups (170)

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Moreover, the literature points out that berberine has inhibitory effects on four key enzymes related to the pathogenesis of Alzheimer s disease: monoamine oxidase B (MAO-B), acetylcholinesterase, monoamine oxidase A (MAO-A), and butyrylcholinesterase (Yuan et al., 2019)