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Thus, adipocytes have a major role in preventing the ectopic accumulation of fat in organs such as liver, skeletal muscle, heart, and pancreas [80]

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Oral supplementation with phosphatidylcholine (250 mg of total choline from food plus 250 mg of supplemental phosphatidylcholine) has been found to result in detectable concentrations of trimethylamine and trimethylamine N-oxide (TMAO) in the blood (23)

doi: 10.1016/j.freeradbiomed.2010.11.029

Elderly persons tend to have a higher adipose to muscle tissue ratio, and this is therefore one reason why the half-life of some drugs, such as diazepam, is greater in the elderly