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Description
In this syndrome, the lack of lipoic acid, due to the defective activity of lipoic synthase, causes the subsequent impairment in lipoid acid-dependent enzymes, such as PDH and KDH [126]
The primary exposure mechanism of PM is inhalation 2
Drug Metab Dispos 35:14551458
For exogenous antioxidants, the unidirectional two-sample MR analysis exhibited a nominal relationship between the serum retinol level and non-small-cell lung cancer risk (OR = 0.29, 95% CI: 0.110.76, p = 0.011)
and UGT enzyme-efflux transporter-uptake transporters coupling
