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This view for the first time substantiated the seed and soil theory in proposing possible influential factors on the compatibility between cancer cells and the colonized organ, but also negated the seed and soil theory in attributing the metastasis organotropism purely to anatomical differences or, in other words, by chance (Fig

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Heat shock proteins such as Hsp20/alpha crystallin family protein are upregulated, reinforcing their role in stabilizing proteins against drought-induced denaturation (Sun et al., 2002)

[Google Scholar] 61.Hiraoka Y., Kishimoto C., Kurokawa M., Ochiai H., Sasayama S

Erastin, a well-known ferroptosis inducer, inhibits system Xc and blocks voltage-dependent anion channels, thereby activating p53 and inducing ferroptosis [149, 150]