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4.5 Gutkidney axis regulation The gutkidney axis refers to the bidirectional interaction between the intestinal microbiota and the kidneys, which plays an increasingly recognized role in CKD progression (43, 44)
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Significantly elevated Hcy associated with the 677TT variant appears to trigger hypermethylation via an alternative B2 dependent rescue pathway (Fryar-Williams, 2016)
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