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While there is no evidence of common structural or functional brain alterations in PAIS, probably due to its heterogeneous origin and lack of conceptualization, ME/CFS has been extensively studied with MRI (magnetic resonance imaging), as recently reviewed by Nelson et al

PLoS ONE 10:e0124844 [DOI] [PMC free article] [PubMed] [Google Scholar]

Particularly in the context of liver cancers, PCSK9 is suggested to engage in complex interactions between antitumor immunity and lipid metabolism, and careful therapeutic approaches may enable effective use of PCSK9 inhibition strategies to curtail cancers of this organ (Alannan et al., 2022)

There was also a statistically non-significant trend (p = 0.09) for greater relative change in lactate threshold in both GPLC groups (1 g, 10.3%

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