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Besides, conjugation of INH with vitamin B6 (pyridoxal and pyridoxal 5-phosphate) leads to the depletion of pyridoxal 5-phosphate in both humans and lab animals61, 136, INH has also been found to reduce the plasma concentrations of calcium and phosphate ions

Temperature-controlled shipping is equally vital, as exposure to heat during transit can degrade the peptide, compromising its potency and potentially requiring dosage adjustments

Since a specific inhibitor was available for GCLC, we focused on this protein and studied the effect of GCLC inhibition with BSO alone or in combination with commonly used chemotherapeutics on survival of BL cells

68 Although the concentration of free copper in cells is almost negligible, it still has a potentially detrimental effect on cell membranes, proteins, and nucleic acids

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