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Its produced by the body and plays a crucial role in protecting cells from oxidative stress the same process that causes aging, inflammation, and tissue damage

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Exposure to the drug induced a mitochondria-independent mode of cell death due to the induction of reactive oxygen species (ROS) through erastin-mediated activation of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase

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Eur J Cardiothorac Surg 2000;18:34852

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[DOI] [PMC free article] [PubMed] [Google Scholar] 2.Kiokias S., Proestos C., Oreopoulou V

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