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Arduini A, Dottori S, Sciarroni AF, Corsico N, Morabito E, Arrigonimartelli E, Calvani M (1995) Effect of propionyl-l-carnitine treatment on membrane phospholipid fatty-acid turnover in diabetic rat erythrocytes

Measurement of Carnitine, TMAO, -butyrobetaine, d9-carnitine, d9-TMAO, and d9--butyrobetaine Sample preparation and quantification for carnitine and TMAO in healthy volunteers Fifty microliters of plasma and 50 L urine samples were extracted with 450 L and 950 L methanol containing 200 ng/mL isotopically labeled internal standards (d3-carnitine and d9-TMAO) respectively, and the extraction was performed using the Geno/Grinder 2010 (SPEX SamplePrep., Metuchen, NJ, USA) at 1000 rpm for 3 min

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This occurs in kidney, liver and brain [5]

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