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Stress and Hormone Regulation: It acts as a modulator of the endocrine system, with evidence suggesting it reduces cortisol levels and influences the release of luteinizing hormone (LH) and growth hormone (GH)

Epithalon has not been studied in pregnancy, and reproductive toxicity data is limited

[DOI] [PubMed] [Google Scholar] 19.Chia CW, Carlson OD, Kim W, et al

Given that the intestinal epithelial barrier function was found to be positively regulated by activation of the intestinal cannabinoid type 1 receptor (CB1R) 27 , we treated mice with ACEA (arachidonyl-2-chloroethylamide), a selective CB1R agonist 28 during the autoimmune noninflammatory pre-phase of CIA from day 17 to day 27 after immunization

The same culture supernatants lacking LMB-7 were used as a negative control