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Surprisingly, when AML12 cells internalized either EV-NC or EV-HFD and were subsequently treated with H 2 O 2 , a significant increase in cell viability and a reduction in ROS levels were observed compared to the group treated with H 2 O 2 alone

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2.4.4 The association between microplastics and central nervous system neoplasms Toxicological testing and metabolic profiling results demonstrate that nano/micron polystyrene materials (n/mPS) exert significant toxic effects on SH-SY5Y human neuroblastoma cells, with enhanced toxicity under oxidative conditions ultimately leading to cytotoxicity and metabolic disturbances (59), revealing microplastics intervention in tumor cells

Wang D, Tan G, Wang H, Chen P, Hao J, Wang Y