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For instance, RSL3 enhances PD-1 blockade efficacy by targeting GPX4 to induce lipid peroxidation in CRC cells

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Recent advances of using exosomes as diagnostic markers and targeting carriers for cardiovascular disease

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The membrane was incubated with 5% non-fat dry milk for 1 h at room temperature and then incubated overnight at 4 C with primary antibodies against GSK-3 (1:1000), PP2A alpha + beta (1:1000), and -actin (1:10,000)

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Some of these studies have combined functional analyses of mitochondrial bioenergetics in PBMCs with either metabolomic studies to identify differentially-expressed mitochondrial-based molecular profiles [62] or genetic signatures [63] as markers for predicting disease progression in MASLD

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