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Trimethylamine-N-oxide is an independent risk factor for hospitalization events in patients receiving maintenance hemodialysis
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TMAO appears to induce renal inflammation, apoptosis, oxidative stress, and disrupt kidney function

Bioactive compounds in garlic ( Allium sativum L.) as a source of antioxidants and its potential to improve the immune system: a review

PMID: 31472821 3 A Rare Treatable Cause of Cardiomyopathy: Primary Carnitine Deficiency

In a state of mitochondrial dysfunction, partially metabolized fatty acids can build up inside the mitochondria, forming toxic acyl-CoA compounds that inhibit essential enzymes and cause severe oxidative stress
