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Crystallographic, electron microscopic, biochemical and cellular localization analyses revealed that the GAS7 F-BAR domain possesses unique hydrophilic loops that contribute to two-dimensional sheet formation of GAS7 on flat membranes of phagocytotic cup, indicating that the sheet-like assembly of GAS7 is essential for phagocytosis

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In some embodiments, the target antigen locates on the cell membrane and facilitates internalization of the CpG-Ab immunoconjugate into the cytosol upon binding to the CpG-Ab immunoconjugate

Except for GSTK17 GST isozymes were upregulated by 802,500,000 folds than those in the control group (Fig

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