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Description
extracellular matrix signalling

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As the dominant G-actin sequestering protein in mammalian cells, TB-500 binds globular actin with high affinity (Kd ~0.5 M) through a sophisticated triple-contact mechanism involving Lys-3, Lys-18, and Lys-38 residues, preventing spontaneous actin polymerization while maintaining a readily mobilizable reservoir for rapid cytoskeletal reorganization

Glutathione reductase (GR) is a flavoenzyme whose main function is to catalyze the reduction of oxidized glutathione (GSSG) to reduced glutathione (GSH), playing a crucial role in the redox balance of cells.

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