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These studies reveal a central role of HIFs in the adaptive responses to hypoxia such as the increase in erythropoiesis and the promotion of a glycolytic switch towards more oxygen-efficient pathways, or an increase in the levels of extracellular adenosine production and signalling 15

prepared a SLNs based DDS using a melt-emulsion method to encapsulate proanthocyanidins and that showed it lowered oxidative stress by reducing ROS production

10.7554/eLife.44210 86

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