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For instance, in the work of He et al., virtual screening and molecular modeling were utilized to identify ligands that interact with CagA protein to discover potential natural compound candidates (He et al., 2022a)

These results characterize the role of OxrA in as a core regulator of oxidative stress resistance and fungal pathogenesis (Figure 7) [31]

These compounds include DL-threo--benzyloxyaspartate (DL-TBOA), pyrrolidine-2,4-dicarboxylic acid (PDC) and dihydrokainate (DHK) [214, 215]

Autophagic cell death, characterized with upregulation of Beclin 1 and elevated LC3 cleavage, is also induced by ISA in ovarian cancer cells, which was found to be associated with PEA-15 upregulation and following ERK activation (Weng et al., 2016)

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