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Heteroplasmic mtDNA Mutation Segregation in Somatic Cells and Tissues Heteroplasmic mtDNAs also segregate in somatic cells and tissues and this greatly complicates phenotypic predictions in patients

Anti-LC3B (D11), anti-GAPDH antibodies, and senescence -galactosidase staining kit were purchased from Cell Signaling Technology (Danvers, MA, USA)

Studies indicate that mitochondrial metabolic reprogramming significantly influences the pathophysiological progression of DKD

Abstract Late-life depression (LLD), a growing public health challenge in aging societies, profoundly impacts physical and mental health by exacerbating cognitive decline, functional disability, and comorbid chronic diseases

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