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Useful angiogenesis endpoints include: VEGF expression VEGFR2 pathway markers CD34 staining factor VIII staining endothelial cell response new vessel organisation blood flow related tissue markers A 2009 study looked at BPC-157 in relation to VEGF expression and angiogenic behaviour across cell culture and tissue injury models

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These results suggest a lack of disease-modifying effects in early-stage PD patients (Pagano et al., 2022)