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Runx2/Osterix pathway: Upregulation of Runx2 (osteogenic differentiation core transcription factor) and Osterix expression induces directed differentiation of bone marrow mesenchymal stem cells into osteoblasts and increases new bone formation

Testicular histology was assessed using Hematoxylin-Eosin staining to observe seminiferous tubule morphology, and a Johnsons score was applied to quantify spermatogenic function based on a 10-point scale

216,217,218,219 Supplementation of exogenous sodium lactate (NaLa) to B-cell adapter for PI3K (BCAP)-deficient bone marrow-derived macrophages (BMDM) reverses the downregulated Arginase-1 (ARG1) and Krppel-like factor 4 (KLF4) expression caused by BCAP deficiency

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