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Red-flag symptoms such as severe abdominal pain, persistent vomiting, or jaundice require immediate cessation and urgent medical attention
Secondary hypogonadism results in low serum testosterone and unopposed estrogen effect from increased conversion of adrenal precursors to estrogens (24)

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References G Noctor, G Queval, A Mhamdi, S Chaouch, CH Foyer

For example, ICAM-1 is positively associated with the incidence of acute cardiovascular events
