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We are getting heart disease first or we are getting a hip fracture and dying a year later, etc., etc

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Research elucidates a novel HMGB1-mediated inflammatory pathway in Non-Alcoholic Fatty Liver Disease (NAFLD), revealing a redox signaling mechanism where ONOO-, formed through NADPH oxidase activation, plays a pivotal role in TLR-4 activation and cytokine release (150)

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doi: 10.1056/NEJMoa0810818