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doi: 10.3389/freae.2024.1430294 Received 09 May 2024 Accepted 02 July 2024 Published 19 July 2024 Volume 2 - 2024 Edited by Raffaele Frazzi, Azienda Unit Sanitaria Locale - IRCCS di Reggio Emilia, Italy Reviewed by Lise Lotte Hansen, Aarhus University, Denmark Xin Liu, University of Texas Southwestern Medical Center, United States Updates Copyright 2024 Xu, Guo, Liu, Hu and Li

This review attempts to discuss recent insights into skin and gut microbial communities, including their interaction with host metabolism and the immune system, their composition and functional association with human health and psoriasis, and diagnostic or therapeutic approaches targeting these communities, with a focus on examining the evolution of microbiological intervention and reviewing potential microbial biomarkers associated with the occurrence, transmission, flare-up and severity of the disease, in addition to describing the therapeutic potential of modulating microbial compositions and skin immunology