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and fibrotic lesions mainly appear in latent TB but also in some active disease and are composed almost entirely of fibroblasts, with a minimal number of macrophages [129]

However, it is important to have realistic goals and expectations for treatments

Additionally, Sun et al
doi: 10.1001/jamaneurol.2014.131

Its a serious condition because it reduces oxygen transport around the body and the most common causes by far are vitamin B12 and folate deficiency (Hariz and Bhattacharya, 2023)