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Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia

Its effects on the HGF/c-Met pathway, while beneficial for neural repair, require careful consideration regarding long-term use

WWOX tuning of oleic acid signaling orchestrates immunosuppressive macrophage polarization and sensitizes hepatocellular carcinoma to immunotherapy

10.1001/archneurol.2011.235 202 HuangY.ShiX.LiZ.ShenY.ShiX.WangL.et al

This can manifest as redness, swelling, and sometimes pain