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Description
doi: 10.1016/j.clnu.2024.12.030
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The mechanosensitive ion channel Piezo1 is inhibited by the peptide GsMTx4
153 As a compensatory mechanism, IAPP may activate HIF-1/6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) to protect against oligomer toxicity, thus delaying the loss of cells but at the cost of impairing cell function
