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doi: 10.1113/jphysiol.2009.169300
The glutathione peroxidase pathway is further regulated by System Xc-, an amino acid antiporter consisting of a disulfide-linked heterodimer of xCT/SLC7A11 and SLC3A2/4F2hc/CD98, and is inhibited by the ferroptosis inducer erastin (4)
It is often called the master antioxidant because it plays a central role in antioxidant defense and detoxification, helping protect cells from daily damage
