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Lack of historical evidence to support folic acid exacerbation of the neuropathy caused by vitamin B12 deficiency

H., Nair S., Rousseau E., et al
This article explores evidence-based B12 dosing for neuropathic pain, mechanisms of nerve repair, deficiency recognition, and when to seek NHS medical assessment for proper diagnosis and monitoring

Under normal conditions, NNMT activity can consume substantial amounts of both nicotinamide and SAM, particularly in metabolically active tissues or during periods of metabolic stress

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