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This energetic role is usually considered in the context of the specific vulnerability to TD of tissues with high energy demand, such as the heart and the brain

Moreover, our results suggest that at oxygen concentrations of 20% the reoxidation of Mia40 can in vivo be efficiently driven by the direct interaction of Erv1 and oxygen

Tsarouchas et al., 2018)

Whether or not ergothioneine supplementation (25 mg given three times a week for 52 weeks) may be beneficial in delaying or reversing cognitive decline is the subject of an ongoing clinical trial in elderly individuals with mild cognitive impairment (79)

Gutierrez D, Weinstock A, Antharam VC, Gu H, Jasbi P, Shi X, et al