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Such a pattern is not found with metabolism of other substrates including glucose and acetate [122, 123]

Mar 2021;28(3):809-815

Finally, we highlight major limitations in the current evidencesuch as heterogeneous dosing regimens, the scarcity of long-term clinical data, and insufficient mechanistic validation under MASLD conditionsand propose directions for future translational research

Some researchers think ALA has potential weight-loss benefits because it suppresses an enzyme called AMP-activated protein kinase (AMPK), which plays a role in appetite

For example, cerebrovascular disease is a cause of stroke, and peripheral artery disease can restrict activities and result in loss of limbs