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Description
SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients

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Hence, EGCG protects mitochondrial respiratory enzymes and decreases mitochondrial ROS production in cisplatin-induced nephrotoxicity (Sahin et al., 2010

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The research doesn't suggest harm from longer cycles, but periodic breaks are a reasonable precaution given limited long-term human data
