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The frequency-selective RF pulses were also responsible for a dephasing of unwanted signals, requiring significant gradient spoiling that, in turn, increases the minimum TE for PRESS acquisitions when compared with the other unedited techniques like STEAM and SPECIAL [40]

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Similarly, inflamed tissues release specific chemicals (chemokines) that guide neutrophils along the concentration gradient 27,28,29

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Nevertheless, the study fails to clarify differences in serum PCS levels among PBC patients at different disease stages, uses non-human primary Kupffer cells in vitro , and does not evaluate the safety threshold for clinical PCS supplementation, which limits its therapeutic translation

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By eliminating these senescent cells, FOXO4-DRI alleviates the inflammatory microenvironment and shows potential to prevent the tumor-like aggressiveness and high recurrence rate characteristic of keloids

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Map of human MHC

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