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Firstly, we found that lactate was taken up and oxidized in mitochondria, fueling the TCA cycle and enhancing -KG-DNMT3B-SOX2-mediated stemness potentials
Collier, The University of North Carolina School of Medicine
The metabolism of amino acids, particularly glutamine, in AML cells represents a vital aspect of the cellular metabolism that supports rapid cell proliferation and survival under continuous stress conditions
doi: 10.1126/science.1209038
