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10.1172/JCI116092 232 NishimotoM.MizunoR.FujitaT.IsshikiM

363 Recently, Zeldin and coworkers found that endothelial cells from CYP4F2 transgenic mouse exhibited a twofold increase in levels of 20-HETE, increased growth and tube formation with upregulation of VEGF and the prooxidant enzyme NADPH oxidase subunits (gp91phox and p47phox)

DNMT3A and TeT2 in the Pre-Leukemic Phase of Hematopoietic Disorders

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When the aforementioned treatments are unavailable, systemic therapy becomes the primary choice [7], encompassing chemotherapy, targeted therapy, and immunotherapy [8]