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The specificity requirement matters too

Worms, flies, mammals (rodents, primates, cats, minipig, and dogs), and other animal species (such as drosophila and zebrafish) have been used in PD research [129]

Despite species-specific differences in the life cycles, tissue tropism and clinical presentation, they are all known to modulate the human host's immune system (7)

Results indicated that n = 79 out of n = 172 child subjects, had levels of mercury in their urine samples below the permissible limit [10 g/L], whereas n = 93 child subjects had the levels higher than the permissible limit