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Other Firmicutes genera such as Anaerococcus , Roseburia and Ruminococcus have also been linked to TMA formation (67)

Disorders of renal carnitine metabolism may also have a negative effect on cardiac function

Carnitine supplementation is actively used for the treatment of CFS, fatigue caused by chemotherapy, fatigue in the elderly, and fatigue caused by different neurological diseases [19]

Despite its short duration, the current study had significant results in its composite endpoint, but did not significantly impact the physical activity (6-min walk test), QoL, and mTOR phosphorylation which may have improved with prolonged supplementation

Urine was collected within 2 h of blood sampling