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Individuals who may be considered appropriate candidates include: Persistent fatigue or low energy despite adequate rest Frequent travel with dehydration, jet lag, or recovery issues High physical, cognitive, or professional stress levels Difficulty tolerating oral supplements or poor gastrointestinal absorption Need for hydration support under medical supervision Interest in supportive wellness care alongside doctor-guided treatments Each case is assessed individually

The reduced Iba-1 histological staining was also consistent with the findings from western blot analysis of Iba-1 expression (Fig

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Regardless of the mechanisms of cholesterol enrichment, VSMCs compared to macrophages are inefficient at lysosomal processing and trafficking of cholesterol (152,153) and express much less ABCA1(154), which all contribute to impaired cholesterol efflux (155)

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