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Pharmacodynamics, pharmacokinetics and safety of multiple ascending doses of the novel dual glucose-dependent insulinotropic polypeptide/glucagon-like peptide-1 agonist RG7697 in people with type 2 diabetes mellitus

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Briefly, Fe3+ is deoxygenated to catalytically active Fe2 + and released into the cytoplasmic labile iron pool (LIP) to be utilized or stored as ferritin in the cell

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