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Small intestinal mucin is less dense and penetrable to bacteria

The mechanical activation of ENaC is, in part, predicated on N-glycosylation of asparagines, which are thought to act as anchoring points for extracellular tethers that interact with the extracellular matrix and/or the glycocalyx (16, 137)

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This matters because incorrect reconstitution can lead to either subtherapeutic dosing or excessive concentrations that may affect stability

Opportunities 3.3.1
