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Hence, the low levels of thiomethyl metabolites observed after APAP exposure are probably associated to the limited cytochrome P450 capabilities of in vitro models to generate NAPQI metabolites via CYP2E compared to in vivo hepatocytes
(D) Western blot analysis to measure SLC25A39 protein levels in RKO and DLD-1 cells, treated as indicated

doi: 10.3390/antiox9111070 64 van ZuurenEJAlbustaAYFedorowiczZCarterBPijlH

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