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There are great concerns that many children in low and middle-income countries fail to reach their developmental potential due to poverty-related factors such as malnutrition, micronutrient deficiencies, parental illiteracy, and lack of stimulation and learning opportunities.47 Results from our study will provide a valuable contribution to the field of early risk and development in disadvantaged children and their families, and may also help to further integrate the Government of Nepal programme on the first 1000 golden days

2 Growth Factors Treatment with IGF-I peptides improves function of the remnant gut following small bowel resection in rats (Lemmey et al., 1994)Rodent study comparing IGF-I with the binding-protein-resistant analogs LR3IGF-I and des(1-3)IGF-I, showing selective anabolic/absorptive effects on gut tissue